About 19 results found for searched term "GSK-3β inhibitor 3" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3054 | TDZD-8 | GSK-3 |
| GSK-3β Inhibitor I; NP 01139 | ||
| TDZD-8 is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC. | ||
| M43380 | GSK-3β inhibitor 13 | GSK-3 |
| GSK-3β inhibitor 13 is an orally active and potent GSK-3β inhibitor with blood-brain permeability. | ||
| M49758 | GSK-3β inhibitor 3 | GSK-3 |
| GSK-3β inhibitor 3 is a potent, selective, irreversible and covalent inhibitor of Glycogen Synthase Kinase 3β (GSK-3β), with an IC50 of 6.6 μM. | ||
| M2304 | TWS119 | GSK-3 |
| TWS119 is a GSK-3β inhibitor with IC50 of 30 nM. | ||
| M2405 | AR-A014418 | GSK-3 |
| GSK-3β Inhibitor VIII | ||
| AR-A014418 is an ATP-competitive, and selective GSK3β inhibitor with IC50 and Ki of 104 nM and 38 nM, without significant inhibition on 26 other kinases tested. | ||
| M3691 | IM-12 | GSK-3 |
| IM-12 is a potent and selective GSK-3β inhibitor with IC50 of 53 nM, which also enhances canonical Wnt signalling. | ||
| M10108 | Indirubin-3'-monoxime | GSK-3 |
| I3MO | ||
| Indirubin-3'-monoxime is a potent GSK-3β inhibitor with IC50 of 22 nM, and inhibits Cdk5/p35, Cdk1/cyclin-B and Cdk2/cyclin-E with IC50s of 100, 180, 250 nM. | ||
| M10531 | BRD3731 | GSK-3 |
| BRD3731 is a selective GSK3β inhibitor, with IC50s of 15 nM and 215 nM for GSK3β and GSK3α, respectively. | ||
| M14837 | GSK-3β inhibitor 1 | GSK-3 |
| GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM. | ||
| M29819 | ZLWH-23 | AChR/AChE |
| ZLWH-23 is a selective AChE inhibitor (IC50=0.27 μM) with GSK-3β inhibitory property (IC50=6.78 μM). ZLWH-23 possesses selectivity for AChE over BChE (IC50=20.82 μM) and for GSK-3β over multi-kinases. ZLWH-23 has the potential for the research of Alzheimer's disease. | ||
| M49733 | AChE/BACE1/GSK3β-IN-1 | Gamma-secretase/Beta-secretase |
| AChE/BACE1/GSK3β-IN-1 is an orally active triple inhibitor of AChE/BACE1/GSK3β. | ||
| M49734 | AChE/GSK-3β-IN-1 | AChR/AChE |
| AChE/GSK-3β-IN-1 is a potent, dual AChE/GSK-3β inhibitor with IC50 values of 1.2, 149.8 and 22.4 nM for hAChE , hBChE and hGSK-3β, respectively. | ||
| M49738 | GSK-3β inhibitor 15 | Tau Protein |
| GSK-3β inhibitor 15 is a GSK-3β inhibitor (IC50: 3.4 nM). | ||
| M49746 | GSK3β inhibitor II | GSK-3 |
| GSK3β inhibitor II is an inhibitor of GSK3β. | ||
| M49757 | GSK-3β inhibitor 2 | GSK-3 |
| GSK-3β inhibitor 2 is a potent, selective and orally active GSK-3β inhibitor with an IC50 of 1.1 nM. | ||
| M49759 | GSK-3β inhibitor 6 | GSK-3 |
| GSK-3β inhibitor 6 is a potent GSK-3β inhibitor with an IC50 value of 24.4 μM. | ||
| M49760 | GSK-3β inhibitor 7 | GSK-3 |
| GSK-3β inhibitor 7 is a GSK-3β inhibitor with an IC50 value of 5.25 μM. | ||
| M49761 | GSK-3β inhibitor 8 | GSK-3 |
| GSK-3β inhibitor 8, a thiophenacil derivative, is an effective and selective inhibitor of GSK-3β (IC50=64 nM). | ||
| M49769 | ZDWX-25 | GSK-3 |
| ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. | ||
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